Neuropsychiatric Adverse Events in Brodalumab Psoriasis Studies
نویسندگان
چکیده
منابع مشابه
Varenicline, smoking cessation, and neuropsychiatric adverse events.
OBJECTIVE In 2009, the U.S. Food and Drug Administration issued a black box warning for varenicline regarding neuropsychiatric events. The authors used data from randomized controlled trials and from a large Department of Defense (DOD) observational study to assess the efficacy and safety of varenicline. METHOD The authors reanalyzed data from the 17 placebo-controlled randomized controlled t...
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There have been concerns that oseltamivir causes neuropsychiatric adverse events (NPAEs). We analyzed the association of age and gender with NPAEs in patients treated with oseltamivir using a logistic regression model. NPAE data were obtained from the U.S. Food and Drug Administration Adverse Event Reporting System (2004 to 2013). The lower limit of the reporting odds ratio (ROR) 95% confidence...
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BACKGROUND Psoriasis is a chronic inflammatory disease that may be associated with increased risk of cardiovascular events, including cardiovascular mortality, myocardial infarction, and stroke. METHODS AND RESULTS We searched the MEDLINE, EMBASE, and Cochrane Central Register databases for relevant studies in English between January 1, 1980, and January 1, 2012. Extraction was by 3 independe...
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Asthma is the most common chronic disease of childhood. It is associated with significant morbidity and costs including missed time from school and work for children and their parents. For those children ⩾5 years of age with persistent symptoms or frequent exacerbations, inhaled corticosteroids (ICS) provide an effective and safe treatment, at least at low doses. However, parents are often conc...
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OBJECTIVES Dolutegravir (DTG), a second-generation integrase strand transfer inhibitor (INSTI), is now among the most frequently used antiretroviral agents. However, recent reports have raised concerns about potential neurotoxicity. METHODS We performed a retrospective analysis of a cohort of HIV-infected patients who had initiated an INSTI in two large German out-patient clinics between 2007...
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ژورنال
عنوان ژورنال: SKIN The Journal of Cutaneous Medicine
سال: 2017
ISSN: 2574-1624
DOI: 10.25251/skin.1.supp.24